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  • ÑÑÚ¸ãÕ. ÀÇ·áºÐÀïÀÇ ÇÕ¸®Àû ÇØ°á¹æ¾È¿¡ °üÇÑ ¿¬±¸/ , ñéäçÓÞùÊÎè ú¼ïÙÓÞùÊê ¼®»çÇÐÀ§³í¹® [2000]
  • Adverse events in surgical patients in Australia.

    • Kable AK, Gibberd RW, Spigelman AD.
    • Int J Qual Health Care. 2002 Aug;14(4):269-76.

    • Centre for Clinical Epidemiology and Biostatistics, School of Medical Practice, Faculty of Health, University of Newcastle, Newcastle, New South Wales, Australia.
    • OBJECTIVE

      • To determine the adverse event (AE) rate for surgical patients in Australia.
    • DESIGN

      • A two-stage retrospective medical record review was conducted to determine the occurrence of AEs in hospital admissions. Medical records were screened for 18 criteria and positive records were reviewed by two medical officers using a structured questionnaire.
    • SETTING

      • Admissions in 1992 to 28 randomly selected hospitals in Australia.
    • STUDY PARTICIPANTS

      • Five hundred and twenty eligible admissions were randomly selected from in-patient database in each hospital. A total of 14,179 medical records were reviewed, with 8747 medical and 5432 surgical admissions.
    • MAIN OUTCOME MEASURES

      • Measures included the rate of AEs in surgical and medical admissions, the proportion resulting in permanent disability and death, the proportion determined to be highly preventable, and the identification of risk factors associated with AEs.
    • RESULTS

      • The AE rate for surgical admissions was 21.9%. Disability that was resolved within 12 months occurred in 83%, 13% had permanent disability, and 4% resulted in death. Reviewers found that 48% of AEs were highly preventable. The risk of an AE depended on the procedure and increased with age and length of stay.
    • CONCLUSION

      • The high AE rate for surgical procedures supports the need for monitoring and intervention strategies. The 18 screening criteria provide a tool to identify admissions with a greater risk of a surgical AE. Risk factors for an AE were age and procedure, and these should be assessed prior to surgery. Prophylactic interventions for infection and deep vein thrombosis could reduce the occurrence of AEs in hospitals.
    • http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=12201185&query_hl=22&itool=pubmed_docsum
    • http://intqhc.oxfordjournals.org/cgi/reprint/14/4/269
  • A comparison of iatrogenic injury studies in Australia and the USA. I: Context, methods, casemix, population, patient and hospital characteristics.

    • Thomas EJ, Studdert DM, Runciman WB, Webb RK, Sexton EJ, Wilson RM, Gibberd RW, Harrison BT, Brennan TA.

    • Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. eric.thomas@uth.tmc.edu

    • OBJECTIVE

      • To better understand the differences between two iatrogenic injury studies of hospitalized patients in 1992 which used ostensibly similar methods and similar sample sizes, but had quite different findings. The Quality in Australian Health Care Study (QAHCS) reported that 16.6% of admissions were associated with adverse events (AE), whereas the Utah, Colorado Study (UTCOS) reported a rate of 2.9%.

    • SETTING

      • Hospitalized patients in Australia and the USA.

    • DESIGN

      • Investigators from both studies compared methods and characteristics and identified differences. QAHCS data were then analysed using UTCOS methods.

    • MAIN OUTCOME MEASURES

      • Differences between the studies and the comparative AE rates when these had been accounted for.

    • RESULTS

      • Both studies used a two-stage chart review process (screening nurse review followed by confirmatory physician review) to detect AEs; five important methodological differences were found: (i) QAHCS nurse reviewers referred records that documented any link to a previous admission, whereas UTCOS imposed age-related time constraints; (ii) QAHCS used a lower confidence threshold for defining medical causation; (iii) QAHCS used two physician reviewers, whereas UTCOS used one; (iv) QAHCS counted all AEs associated with an index admission whereas UTCOS counted only those determining the annual incidence; and (v) QAHCS included some types of events not included in UTCOS. When the QAHCS data were analysed using UTCOS methods, the comparative rates became 10.6% and 3.2%, respectively. CONCLUSIONS: Five methodological differences accounted for some of the discrepancy between the two studies. Two explanations for the remaining three-fold disparity are that quality of care was worse in Australia and that medical record content and/or reviewer behaviour was different.

    • http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=11079216&query_hl=10&itool=pubmed_DocSum

  • A comparison of iatrogenic injury studies in Australia and the USA. II: Reviewer behaviour and quality of care.

    • Runciman WB, Webb RK, Helps SC, Thomas EJ, Sexton EJ, Studdert DM, Brennan TA.
    • Department of Anaesthesia and Intensive Care, University of Adelaide, Australia. wrunciman@bigpond.com
    • OBJECTIVE

      • To better understand the remaining three-fold disparity between adverse event (AE) rates in the Quality in Australia Health Care Study (QAHCS) and the Utah-Colorado Study (UTCOS) after methodological differences had been accounted for.
    • SETTING

      • Iatrogenic injury in hospitalized patients in Australia and America.
    • DESIGN

      • Using a previously developed classification, all AEs were assigned to 98 exclusive descriptive categories and the relative rates compared between studies; they were also compared with respect to severity and death.
    • MAIN OUTCOME MEASURES

      • The distribution of AEs amongst the descriptive and outcome categories.
    • RESULTS

      • For 38 categories, representing 67% of UTCOS and 28% of QAHCS AEs, there were no statistically significant differences. For 33, representing 31% and 69% respectively, there was seven times more AEs in QAHCS than in UTCOS. Rates for major disability and death were very similar (1.7% and 0.3% of admissions for both studies) but the minor disability rate was six times greater in QAHCS (8.4% versus 1.3%). CONCLUSIONS: A similar 2% core of serious AEs was found in both studies, but for the remaining categories six to seven times more AEs were reported in QAHCS than in UTCOS. We hypothesize that this disparity is due to different thresholds for admission and discharge and to a greater degree of under-reporting of certain types of problems as AEs by UTCOS than QAHCS reviewers. The biases identified were consistent with, and appropriate for, the quite different aims of each study. No definitive difference in quality of care was identified by these analyses or a literature review.
    • http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=11079217&query_hl=10&itool=pubmed_DocSum
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