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    • Cardiopulmonary resuscitation of adults in the hospital: a report of 14720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation.

      • Resuscitation. 2003 Sep;58(3):297-308.

      • Peberdy MA, Kaye W, Ornato JP, Larkin GL, Nadkarni V, Mancini ME, Berg RA, Nichol G, Lane-Trultt T.

      • Virginia Commonwealth University's Health System, West Hospital, Richmond, VA 23298, USA.

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        • The National Registry of Cardiopulmonary Resuscitation (NRCPR) is an American Heart Association (AHA)-sponsored, prospective, multisite, observational study of in-hospital resuscitation.

        • The NRCPR is currently the largest registry of its kind.

        • The purpose of this article is to describe the NRCPR and to provide the first comprehensive, Utstein-based, standardized characterization of in-hospital resuscitation in the United States.

        • All adult (>/=18 years of age) and pediatric (<18 years of age) patients, visitors, employees, and staff within a facility (including ambulatory care areas) who experience a resuscitation event are eligible for inclusion in the NRCPR database.

        • Between January 1, 2000, and June 30, 2002, 14720 cardiac arrests that met inclusion criteria occurred in adults at the 207 participating hospitals.

        • An organized emergency team is available 24 h a day, 7 days a week in 86% of participating institutions.

        • The three most common reasons for cardiac arrest in adults were (1) cardiac arrhythmia, (2) acute respiratory insufficiency, and (3) hypotension. Overall, 44% of adult in-hospital cardiac arrest victims had a return of spontaneous circulation (ROSC); 17% survived to hospital discharge. Despite the fact that a primary arrhythmia was one of the precipitating events in nearly one half of adult cardiac arrests, ventricular fibrillation (VF) was the initial pulseless rhythm in only 16% of in-hospital cardiac arrest victims. ROSC occurred in 58% of VF cases, yielding a survival-to-hospital discharge rate of 34% in this subset of patients. An automated external defibrillator was used to provide initial defibrillation in only 1.4% of patients whose initial cardiac arrest rhythm was VF. Neurological outcome in discharged survivors was generally good. Eighty-six percent of patients with Cerebral Performance Category-1 (CPC-1) at the time of hospital admission had a postarrest CPC-1 at the time of hospital discharge.

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    • Is cardiopulmonary resuscitation warranted in children who suffer cardiac arrest post trauma?

      • Pediatr Emerg Care. 2007 Apr;23(4):267-72.

      • Bennett M, Kissoon N.

      • Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.

      • ÃÊ·Ï

        • The use of cardiopulmonary resuscitation (CPR) is accepted universally for patients with cardiovascular compromise. However, outcomes from CPR in subsets of trauma patients may not be as good as initially thought. This article reviews the literature on outcomes from traumatic arrest in both adults and children. Outcomes for adults and children are similar, although the types of injuries may differ. Patients with asystolic arrest at the scene have very poor survival, and those who do survive sustain severe neurological injury. Recognizing that most providers would feel uncomfortable at not attempting resuscitation, the length and degree of aggressiveness of CPR is addressed. Finally, we discuss possible reasons to resuscitate. Organ donation and the ethics of nontherapeutic ventilation and other strategies to increase the donor pool are discussed. We hope to stimulate discussion around a very difficult issue.

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    • Stiell et al., reporting for the Ontario Prehospital Advanced Life Support Study Group (pages 647–656), evaluated the marginal benefit of advanced-life-support training in an emergency-medical-services system previously optimized for rapid defibrillation (response time was eight minutes or less in more than 90 percent of cases). Although the rate of admission to the hospital after a cardiac arrest increased significantly from the rapid-defibrillation phase to the advanced-life-support phase, the rate of survival to hospital discharge did not increase and remained suboptimal at 5 percent. Multivariate predictors of survival included arrests witnessed by bystanders or emergency-medical-services personnel, CPR by bystanders, and rapid defibrillation (the first three links in the chain of survival), but not access to advanced life support.

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